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Effects of exercise on cellular and tissue aging


source: https://www.aging-us.com/article/203051/pdf
ABSTRACT
The natural aging process is carried out by a progressive loss of homeostasis leading to a functional decline in
cells and tissues. The accumulation of these changes stem from a multifactorial process on which both external
(environmental and social) and internal (genetic and biological) risk factors contribute to the development of
adult chronic diseases, including type 2 diabetes mellitus (T2D). Strategies that can slow cellular aging include
changes in diet, lifestyle and drugs that modulate intracellular signaling. Exercise is a promising lifestyle
intervention that has shown antiaging effects by extending lifespan and healthspan through decreasing the
nine hallmarks of aging and age-associated inflammation. Herein, we review the effects of exercise to
attenuate aging from a clinical to a cellular level, listing its effects upon various tissues and systems as well as
its capacity to reverse many of the hallmarks of aging. Additionally, we suggest AMPK as a central regulator of
the cellular effects of exercise due to its integrative effects in different tissues. These concepts are especially
relevant in the setting of T2D, where cellular aging is accelerated and exercise can counteract these effects
through the reviewed antiaging mechanisms.
#health #saúde #exercise #exercicio #deporte #diabetes #heart #aging #envellecemento #science #paper #ciencia
 

Effects of exercise on cellular and tissue aging


source: https://www.aging-us.com/article/203051/pdf
ABSTRACT
The natural aging process is carried out by a progressive loss of homeostasis leading to a functional decline in
cells and tissues. The accumulation of these changes stem from a multifactorial process on which both external
(environmental and social) and internal (genetic and biological) risk factors contribute to the development of
adult chronic diseases, including type 2 diabetes mellitus (T2D). Strategies that can slow cellular aging include
changes in diet, lifestyle and drugs that modulate intracellular signaling. Exercise is a promising lifestyle
intervention that has shown antiaging effects by extending lifespan and healthspan through decreasing the
nine hallmarks of aging and age-associated inflammation. Herein, we review the effects of exercise to
attenuate aging from a clinical to a cellular level, listing its effects upon various tissues and systems as well as
its capacity to reverse many of the hallmarks of aging. Additionally, we suggest AMPK as a central regulator of
the cellular effects of exercise due to its integrative effects in different tissues. These concepts are especially
relevant in the setting of T2D, where cellular aging is accelerated and exercise can counteract these effects
through the reviewed antiaging mechanisms.
#health #saúde #exercise #exercicio #deporte #diabetes #heart #aging #envellecemento #science #paper #ciencia
 
From Source.
Please correct me if I am wrong.

A vaccine passport means that if you have been double jabbed and have Covid you can go to events, but if you have not been double jabbed and don’t have Covid you cannot go to events.

#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Eugenics #Reality #Fact #UNagenda21 #Depopulation #Sterilization #Europe #USA #Earth #World #Food #Africa #Asia #Hispanics #SouthAmerica #India #Pakistan #Medical #Vaccine #Vaccines
 

COVID-19 vaccines may trigger superimmunity in people who had SARS long ago | Science | AAAS

Almost 20 years before SARS-CoV-2, a related and even more lethal coronavirus sowed panic, killing nearly 10% of the 8000 people who became infected. But the 2003 outbreak of severe acute respiratory syndrome (SARS) may have left some survivors with a gift. Former SARS patients who have been vaccinated against COVID-19 appear able to fend off all variants of SARS-CoV-2 in circulation, as well as ones that may soon emerge, a new study suggests. Their formidable antibodies may even protect against coronaviruses in other species that have yet to make the jump into humans—and may hold clues to how to make a so-called pancoronavirus vaccine that could forestall future outbreaks.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 

COVID-19 vaccines may trigger superimmunity in people who had SARS long ago | Science | AAAS

Almost 20 years before SARS-CoV-2, a related and even more lethal coronavirus sowed panic, killing nearly 10% of the 8000 people who became infected. But the 2003 outbreak of severe acute respiratory syndrome (SARS) may have left some survivors with a gift. Former SARS patients who have been vaccinated against COVID-19 appear able to fend off all variants of SARS-CoV-2 in circulation, as well as ones that may soon emerge, a new study suggests. Their formidable antibodies may even protect against coronaviruses in other species that have yet to make the jump into humans—and may hold clues to how to make a so-called pancoronavirus vaccine that could forestall future outbreaks.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 
Former Greater Manchester police sergeant Peter John Meadows trusted the UK Government's Covid-19 vaccination policy. The decision cost him his life. It has taken his two brave daughters, Louise and Lisa, to expose what took place from the time he was vaccinated until he died.

#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Eugenics #Reality #Fact #UNagenda21 #Depopulation #Sterilization #Europe #USA #Earth #World #Food #Africa #Asia #Hispanics #SouthAmerica #India #Pakistan #Medical #Vaccine #Vaccines
 
Beware the genetically modified toxic chemical "sweetener" Aspartame has had it's name changed to Amino Sweet, Nutrasweet, and Equal however here in the UK where there is less awareness and a country where genetically modified products are banned they still openly using the original name.

#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Eugenics #Reality #Fact #UNagenda21 #Depopulation #Sterilization #Europe #USA #Earth #World #Food #Africa #Asia #Hispanics #SouthAmerica #India #Pakistan
 

'Your child will wait for another child to die.' Amid #Covid-19 surge, #Dallas County has no pediatric #ICU beds left, county judge says


Source: https://edition.cnn.com/2021/08/13/us/dallas-county-no-pediatric-icu-beds-left/index.html
"That means if your child's in a car wreck, if your child has a congenital heart defect or something and needs an ICU bed, or more likely if they have Covid and need an ICU bed, we don't have one. Your child will wait for another child to die," Jenkins said. "Your child will just not get on the ventilator, your child will be CareFlighted to Temple or #Oklahoma City or wherever we can find them a bed, but they won't be getting one here unless one clears."
#health #usa #humanRights #hospital #news #Corona #coronavirus #pandemic #children
 

'Your child will wait for another child to die.' Amid #Covid-19 surge, #Dallas County has no pediatric #ICU beds left, county judge says


Source: https://edition.cnn.com/2021/08/13/us/dallas-county-no-pediatric-icu-beds-left/index.html
"That means if your child's in a car wreck, if your child has a congenital heart defect or something and needs an ICU bed, or more likely if they have Covid and need an ICU bed, we don't have one. Your child will wait for another child to die," Jenkins said. "Your child will just not get on the ventilator, your child will be CareFlighted to Temple or #Oklahoma City or wherever we can find them a bed, but they won't be getting one here unless one clears."
#health #usa #humanRights #hospital #news #Corona #coronavirus #pandemic #children
 
#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Vaccine #Vaccines #Eugenics #Reality #Fact #UNagenda21 #Depopulation #Sterilization #Europe #USA #Earth #World
Covid Outbreak Hits Carnival Cruise Despite Every Guest and Staff Member Being ‘Vaccinated’
 
Seems even a Cambridge education doesn't necessarily protect from Anti-Vax idiocy:

https://twitter.com/RonFilipkowski/status/1423794706388029440

The video is seriously scary. "spent six hours in the foetal position", but "it's just like a cold". Yeah, right.....

See also on the BBC: Covid vaccine refuser died after terrible mistake, says partner

#Covid19 #Coronavirus #education #antivax #vaccines #death #health #UK
 
Seems even a Cambridge education doesn't necessarily protect from Anti-Vax idiocy:

https://twitter.com/RonFilipkowski/status/1423794706388029440

The video is seriously scary. "spent six hours in the foetal position", but "it's just like a cold". Yeah, right.....

See also on the BBC: Covid vaccine refuser died after terrible mistake, says partner

#Covid19 #Coronavirus #education #antivax #vaccines #death #health #UK
 
Seems even a Cambridge education doesn't necessarily protect from Anti-Vax idiocy:

https://twitter.com/RonFilipkowski/status/1423794706388029440

The video is seriously scary. "spent six hours in the foetal position", but "it's just like a cold". Yeah, right.....

See also on the BBC: Covid vaccine refuser died after terrible mistake, says partner

#Covid19 #Coronavirus #education #antivax #vaccines #death #health #UK
 
LED lightbulbs cause headaches and yet the EU is allowed by the people to ban Halogen; why are we so stupid?

#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News
 
Bild/Foto
From source.

Despite 90% of adults / 70% of the full population in Iceland having being vaccinated, Covid cases have recently rocketed. Therefore, the argument for vaccine passports has been completely destroyed.

#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Vaccine #Vaccines #Eugenics #Reality #Fact #UNagenda21 #Depopulation #Sterilization #Europe #USA #Earth #World
 
#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Vaccine #Vaccines #Eugenics #Reality #Fact #UNagenda21 #Depopulation #Sterilization #Europe #USA #Earth #World
Three Presidents Who Opposed Covid Vaccines Have Conveniently Died, Replaced by Pro-Vaxxers
 
#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Reality #Fact
 
#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Reality #Fact
 
OlyWebDiva 🇺🇸 playing with 🔥, running with ✂️ on Twitter.

The FDA is pulling the CDC's COVID test bc it can't distinguish between COVID & the flu. Does that mean it also can't distinguish between COVID & existing human coronavirus strains? Rhinovirus? Have we been hoodwinked into believing common colds = pandemic? Fluffing the numbers?

#CurrentAffairs #Health #Wellbeing #History #Truth #Freedom #Science #Anarchy #Anarchist #Anarchism #Anarchismo #News #Vaccine #Vaccines #Eugenics #Reality #Fact #UNagenda21 #Depopulation #Sterilization
 
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